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ACADEMIC
AFFILIATIONS:
Temple University, Adjunct Faculty, Department of
Film and Media Arts, Jan 2008 - Jun 2014
Drexel University, Research Affiliate Professor, Biomedical
Engineering, Jun 2009 - Jun 2014
PROFESSIONAL
EXPERIENCE:
W.L. GORE
AND ASSOCIATES, Elkton, MD - Flagstaff, AZ
Translational Research Team - Medical Electronics Lead (2018
– Present)
Drove multiple early-stage research, technology assessment, and new
product development efforts. Supported the evolution of Gore’s
digital health strategy as a subject matter expert on medical electronics
and imaging. Provided expertise in electrochemistry, test method development,
nanomaterials, wearable technology, active/smart materials, interventional
therapies, and neurostimulation as a new business developer, inventor,
and innovator.
New Concept Development Group - Bioelectronics Lead Engineer
(2013 – 2018)
Drove multiple early-stage research, technology assessment, and new
product development efforts. Supported the evolution of Gore’s
digital health strategy as a subject matter expert on medical electronics
and imaging. Provided expertise in electrochemistry, test method development,
nanomaterials, wearable technology, active/smart materials, interventional
therapies, and neurostimulation as a new business developer, inventor,
and innovator.
Cardiovascular Imaging Team - Principle Engineer (2012
– 2013)
Targeted hire for development of a disposable cardiovascular ultrasound
imaging catheter. Responsible for analog RF design and ultrasound modelling,
optimization of image quality, noise immunity, electrical safety, minimization
of cross talk, and interfacing to partner imaging platforms.
INDEPENDENT DESIGNER CONSULTANT, Philadelphia,
PA
Medical and Industrial Ultrasound (1997 – Present)
Systems designer specializing in medical and industrial ultrasound including
therapeutic and diagnostic ultrasound, NDT/NDE, and ultrasound measurement
and control applications. Provide technical advice, analysis, and design
support to academic researchers and the ultrasound industry. Experienced
in physical acoustics, RF/analog circuit design, digital hardware design,
custom prototype construction, embedded software applications, and technology
venture evaluation.
Interactive Exhibition Design (2001– Present)
Interactive exhibition designer, installation artist, and adjunct professor
of Physical Computing at Temple University. Have created custom hardware
and software for clients including The Please Touch Museum, Madrid Abierto,
The Independence Seaport Museum, The Gulf Coast Exploreum, and The Franklin
Institute.
QUANTASON
LLC, Philadelphia, PA
VP, System Development and Integration (2009 –
2012)
Headed a team developing a next generation diagnostic ultrasound breast
screening technology. Patented algorithms for detection and localization
and developed approaches for practical implementation. Managed a group
of 7 engineers and physicists. Designed and prototyped specialized skin
contact acoustic sensors. Directed basic research into optimization
and coordinated the integration of the technology into a major medical
partner's imaging platform.
SPECTRASONICS IMAGING INC., Wayne, PA
Director of Research and Development (November 1997
– June 2007)
Founding member of a team which developed several high-powered therapeutic
ultrasound systems. Investigated the use of ultrasound therapy in cardiac
applications. Designed hardware to acquire digitized RF data from a
commercial medical imaging engine. Wrote and administered phase I and
II SBIR grants to develop an ultrasonic prostate cancer detection/biopsy
guidance system. Detection algorithm ran on a SHARC processor network
embedded in a PC platform, DSP code was written in C++, and user interface
was created using Visual C++/MFC. System was interfaced with a commercial
ultrasonic imager and entered clinical trials in October 2000. Applied
for 2 patents related to this technology.
ULTRAFAST INC. Malvern, PA
Senior Staff Scientist (March 1993 - November 1997)
Senior Staff Scientist in charge of ultrasonic research and analog circuit
development. Designed the thin film piezoelectric transducer and HF
analog front-end electronics used in an ultrasonic load-measurement
system. Wrote firmware and user interface software in Borland C++. Modeled
the ultrasonic transducer using PIEZOCAD and developed a model of acoustic
propagation within a fastener for use in house. Applied for 4 PATENTS
related to enhancement of the technology. The detection and excitation
electronics were designed to interface with automated tightening equipment
and were miniaturized and optimized for low power operation.
DREXEL UNIVERSITY Philadelphia, PA
Research Assistant (Oct. 1987 - Oct. 1992)
Ph.D candidate working in the field of Biomedical Ultrasound. Developed
and tested a model of ultrasonic wave propagation in biological tissue-like
media. Project was funded by a two year NSF award. Ph.D. dissertation
focused on including the effects of nonlinear acoustic phenomena into
the propagation model.
PATENTS:
Apparatus, Systems, and Methods for Percutaneous Delivery
of Neurostimulation Arrays
WO2022/225789, Broyles, Stuart; Duncan, Jeff; Friedman, Nathan; Vecchio,
Christopher
14 April 2022.
Transcutaneous Sound Sensor
WO2021/226504, Xu, Minghua; Vecchio, Chris; Squeri, John,
7 May 2021.
Implantable Cardiac Sensor
US Application 20200196876, Minor, David; Vecchio, Chris; Trapp Benjamin.
23 December 2019.
Medical Treatment System Using Measurement Data from Multiple
Sensors
US #11,540,731 Minor, David; Vecchio, Chris; Trapp, Benjamin,
3 January 2023.
Implantable Medical Device with Adjustable Bloodflow
US Application 20200197178, Vecchio, Christopher J.
23 December 2019.
Implantable Devices Capable of Selective Degradation
US Publication 20170196673, Vecchio, Chris; Cully, Edward
11 January 2017.
Method for locating the position of a microcalcification
in a human breast
US #8,622,909 O'Ruanaidh, Joseph; Vecchio, Christopher J;. Rambod, Edmond
7 January 2014.
Method for detecting and locating a target using phase information
US #8,372,006 O'Ruanaidh, Joseph; Vecchio, Christopher J;. Rambod, Edmond
12 February 2013.
Use of Coded Excitation Schemes in the Detection and Location
of a Target in a Human Body
US #8,109,878 O’Ruanaidh, Graff, Vecchio, Rambod and Snukal
7 February 2012.
Non-Invasive Ultrasound Cardiac Pacemaker and Defibrillator
US Application 20100094149 Kohut, Andrew; Kumik, Peter; Lewin, Peter;
Vecchio, Chris
11 September 2009.
Apparatus and method for locating therapeutic seeds implanted
in a human body
US #6,387,036 Bernardi, Richard; Vecchio, Christopher J.,
10 Sept 2002.
Minimizing the effect of bending on ultrasonic measurements
in a load-bearing member
US #6,009,759, Vecchio, Christopher J., Kibblewhite, Ian E.;
4 Jan 2000.
Technique for eliminating ambiguity when making pulse-echo
timing measurements
US #6,009,380 Vecchio, Christopher J., Kotas, Donald E.,
28 Dec 1999.
SELECTED PUBLICATIONS:
"The Potential of Ultrasound in Cardiac Pacing and Rhythm Modulation",
Andrew R. Kohut, Christopher Vecchio, Dan Adam, & Peter A. Lewin,
Expert Review of Medical Devices, August 2016, doi:10.1080/17434440.2016.1217772
"Ultrasound-induced Modulation of Cardiac Rhythm in Neonatal Rat
Ventricular Cardiomyocytes”, Andrew Fleischman, Andrew R. Kohut,
Christopher Vecchio, Youhan Sunny, Christopher R. Bawiec, Peter A. Lewin,
Yasha Kresh, J Appl Physiol (April 9, 2015) doi:10.1152/japplphysiol.00980.2014
“Determination of Vibrating Structure patterns using Acoustic Waves,”
P.A. Lewin, W.A. Berger,
C.J. Vecchio, M.E. Schafer, 9th ASME Engineering Systems Design and Analysis
Conference
ESDA 2008, July 7-9, 2008, Haifa, Israel.
“Excitation Enhanced Imaging for breast cancer detection: in vitro
and in vivo results.“ F. Forsberg, R. J. Ro, W. T. Shi, M. K. Knauer,
K. Sarkar, A. L. Hall, C. Vecchio, R. Bernardi. Proc Era of Hope, DoD
Breast Cancer Research Meet, pp. 60, 2008
“Real-time excitation-enhanced ultrasound contrast imaging.”
Flemming Forsberg, William T Shi, Michael K Knauer, Anne L Hall, Chris
Vecchio, Richard Bernardi, Ultrason Imaging. 2005 Apr ;27 (2): p. 65-74
“A System Integrating HIFU Exposure Capabilities with Multiple
Modes of Synchronous Ultrasonic Monitoring.” Muratore, Robert; Lizzi,
Frederic L.; Ketterling, Jeffrey A.; Kalisz, Andrew; Bernardi, Richard
B.; Vecchio, Christopher J.; Muratore, Robert., AIP Conference Proceedings
(0094-243X)
03/28/2005. Vol.754, p.33-35
“A system integrating HIFU exposure capabilities with multiple modes
of synchronous ultrasonic monitoring.” Muratore R, Lizzi FL, Ketterling
JA, Andrew K, Bernardi RB, Vecchio CJ. In: ter Haar GR, Rivens I, editors.
4th International Symposium on Therapeutic Ultrasound; Kyoto, Japan; 2004
September 18-20. Melville: American Institute of Physics; 2005. p. 33-35.
“Image enhancement by acoustic conditioning of ultrasound contrast
agents.”
William T Shi, Flemming Forsberg, Ronald Bautista, Chris Vecchio, Richard
Bernardi, Barry B Goldberg, Ultrasound Med Biol. 2004 Feb ;30 (2): p.191-198
“HIFU2: Integrated therapeutic diagnostic ultrasound system,”
R. Muratore, J. Ketterling, C. Vecchio, R. Bernardi, M. Knauer, Proc.
3rd Int. Symp. on Therapeutic Ultrasound, pp. 393-398, 2003
“Effect of nonlinearity on lesion formation for high-intensity
focused ultrasound (HIFU) exposures,” Lee, Paul; Lizzi, Frederic
L.; Ketterling, Jeffrey A.; Vecchio, Christopher J., Acoustical Society
of America Journal, Volume 115, Issue 5, pp. 2449-2449 (2001).
Shi WT, Bautista R, Forsberg F, Vecchio C, Bernardi R, Goldberg BB:
”Evaluation of excitation-enhanced ultrasound contrast imaging.”
J Ultrasound
Med 2001; 20: S12.
”Effects of beam asymmetry on ultrasonic thermal lesions. “
Lizzi FL, Deng CX, Coleman DJ, Silverman RH, Bernardi RB, Vecchio CJ.
In: Schneider SC, Levy M, McAvoy BR, editors. Proceedings of the 1999
IEEE Ultrasonics Symposium. New York: Institute of Electrical and Electronics
Engineers; 2000. p. 1423-1426.
Shi WT, Forsberg F, Bautista R, Vecchio C, Bernardi R, Goldberg BB:
”Active enhancement of ultrasound contrast imaging”, Proceedings
of IEEE
International Ultrasonics Symposium, 1893-1896 (2000).
Forsberg F, Bautista R, Shi WT, Vecchio C, Bernardi R, Goldberg BB:
”Excitation enhanced ultrasound contrast imaging.” Ultrasound
Med Biol 2000;
26(S2): A61.
Vecchio, C.J., "Creation of an Intelligent Fastener using Piezoelectric
Thin Film Techniques," Submitted to IEEE Journal of Ultrasonics,
Ferroelectrics, and Frequency Control (1996).
Vecchio, C.J. and Lewin, P.A., "Finite amplitude acoustic propagation
modeling using the extended angular spectrum method," Journal of
the Acoustical Society of America, JASA 95 (5), pp. 2399-2408, 1994.
Vecchio, C.J., Schafer, M.E., and Lewin, P.A., "Prediction of Ultrasonic
Field Propagation through Layered Media using the Extended Angular Spectrum
Method," Ultrasound in Med. and Bio., Vol. 20, No. 8, 1994.
Vecchio, C.J. and Lewin, P.A., "Acoustic Propagation Modeling Using
the Extended Angular Spectrum Method," Proceedings of the 14th Annual
International Conference IEEE Engineering in Medicine and Biology Society,
1992.
“An experimental investigation of fundamental limitations on ultrasonic
field reconstruction”
Vecchio, Chris; Lewin, Peter A.. Proceedings of the Annual Conference
on Engineering in Medicine and Biology (0589-1019) 01/01/1990.p.281-282
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